FILE - This Aug. 10, 2012 file photo shows Todd Akin, Republican candidate for U.S. Senator from Missouri taking questions after speaking at the Missouri Farm Bureau candidate interview and endorsement meeting in Jefferson City, Mo. Akin fought to salvage his Senate campaign Monday, Aug. 20, 2012, even as members of his own party turned against him and a key source of campaign funding was cut off in outrage over the Missouri congressman's comments that women are able to prevent pregnancies in cases of "legitimate rape." (AP Photo/St. Louis Pos-Dispatch, Christian Gooden)
FILE - This Aug. 10, 2012 file photo shows Todd Akin, Republican candidate for U.S. Senator from Missouri taking questions after speaking at the Missouri Farm Bureau candidate interview and endorsement meeting in Jefferson City, Mo. Akin fought to salvage his Senate campaign Monday, Aug. 20, 2012, even as members of his own party turned against him and a key source of campaign funding was cut off in outrage over the Missouri congressman's comments that women are able to prevent pregnancies in cases of "legitimate rape." (AP Photo/St. Louis Pos-Dispatch, Christian Gooden)
Alaina Carnan of Lexington, Ky., works in the Senate campaign office of U.S. Rep. Todd Akin, R-Mo., Tuesday, Aug. 21, 2012 in Chesterfield, Mo. Akin has come under pressure to abandon his Senate compaign after his comments that women's bodies can prevent pregnancies in cases of "legitimate rape". (AP Photo/Bill Boyce)
A campaign sign stands outside the Senate campaign office of U.S. Rep. Todd Akin, R-Mo., Tuesday, Aug. 21, 2012 in Chesterfield, Mo. Rep. Akin has come under pressure to abandon his Senate compaign after his comments that women's bodies can prevent pregnancies in cases of "legitimate rape". (AP Photo/Bill Boyce)
FILE - In this Feb 18, 2012 file photo, Senate candidate Rep. Todd Akin, R-Missouri, waves to the crowd while introduced at a senate candidate forum during a Republican conference in Kansas City, Mo. The two losing candidates in the Republican primary for Missouri's U.S. Senate seat are getting renewed attention after Akin's comments about rape on Sunday, Aug. 19, 2012. (AP Photo/Orlin Wagner, file)
JEFFERSON CITY, Mo. (AP) ? Rep. Todd Akin defied the nation's top Republicans and refused to abandon a Senate bid that has been hobbled by fallout over his comments that women's bodies can prevent pregnancies in cases of "legitimate rape."
Akin took his message to network TV morning shows and conservative talk radio shows, declaring GOP leaders were overreacting by insisting he give up his quest to unseat Democrat Sen. Claire McCaskill of Missouri, and to social media with appeals for donations on his Twitter feed claiming "liberal elites" are trying to push him out of the race.
"I misspoke one word in one sentence on one day, and all of a sudden, overnight, everybody decides, 'Well, Akin can't possibly win,'" he said on a national radio show Tuesday hosted by former Republican presidential candidate Mike Huckabee. "Well, I don't agree with that."
Akin predicted he would bounce back from the political crisis threatening his campaign, including a call from presumptive presidential nominee Mitt Romney to leave the race, and capture a seat that is pivotal to Republican hopes of regaining control of the Senate.
He confirmed that Republican vice presidential candidate Paul Ryan also called to ask him to drop out. But Akin reiterated his decision to stand his ground, saying he refused to be bullied.
"It's not right for party bosses to override" the voters of Missouri, Akin said in an interview on ABC's "Good Morning America" Wednesday. He said he told Ryan that he was thinking things over and that he wants to "do what's right," but that he's not abandoning his race
Nonetheless, he said he would comply with Republican National Committee Chair Reince Priebus's request that he not attend the convention, which starts Monday.
But his bid faces tall obstacles ? chief among them a lack of money and party support.
In a potential sign of his strategy, Akin appealed Tuesday to Christian evangelicals, anti-abortion activists and anti-establishment Republicans. He said he remains the best messenger to highlight respect for life and liberty that he contends are crumbling under the policies of President Barack Obama.
In a new fundraising appeal Wednesday, Akin asserted "the liberal elite" are trying to "keep a strong, pro-life conservative out of the U.S. Senate." The email seeking $5 contributions also criticized his own party establishment, saying: "I have learned that many in the political class will duck and run for cover when faced with the slightest bit of adversity."
If he stays on the ballot, Akin will have to rebuild without any money from the national party and with new misgivings among rank-and-file Republican voters who just two weeks ago propelled him to a comfortable victory in a hotly contested three-way primary.
"I'm in this race for the long haul, and we're going to win it," he told radio host Dana Loesch in St. Louis.
Akin appealed to evangelicals directly during his interview with Huckabee, making allusions to the 9/11 terrorist attacks and focusing on the idea he had only misplaced a single word during a Sunday interview with St. Louis television station KTVI.
But Akin has been roundly criticized both for using the words "legitimate rape" and saying a woman's body has the ability to prevent conception after such an attack.
Hours earlier, Akin posted an online video in which he apologized again for his remarks. Campaign spokesman Ryan Hite said the apology was intended to cover the reference to "legitimate rape" and Akin's assertion that rape victims have a natural defense against pregnancy. The video will run as a 30-second ad on TV stations statewide for several days, Hite said.
Tuesday was the final day in which Akin could withdraw from the race without a court order. As the 5 p.m. deadline to withdraw neared, Republican leaders intensified their pressure on Akin to exit.
Sen. Roy Blunt issued a joint statement Tuesday with all four of Missouri's living former Republican senators ? John Ashcroft, Kit Bond, Jim Talent and John Danforth ? saying "it serves the national interest" for Akin to step aside.
Pointing to the group, Romney said the congressman should "accept their counsel."
A Romney aide said the candidate had been inclined to let Akin make the decision on his own. But after the Missouri lawmakers called for Akin to go, Romney wanted to make his position clear, said the aide, who requested anonymity because the aide was not authorized to publicly discuss Romney's thinking.
Akin provoked the political uproar when he was asked in the KTVI interview whether his general opposition to abortion extends to women who have been raped.
"It seems to me, first of all, from what I understand from doctors, that's really rare. If it's a legitimate rape, the female body has ways to try to shut that whole thing down," Akin said.
It's not clear if Akin's campaign will have the financial support to wage a prolonged advertising battle against McCaskill in the expensive St. Louis and Kansas City markets and the Republican-rich area of southwest Missouri.
The campaign arm of the Senate Republicans has already withdrawn $5 million in advertising planned for the Missouri race. The Karl Rove-backed Crossroads organization pulled its ads too. A fundraiser planned in Washington for next month was called off after all of the dozen GOP senators who had agreed to participate pulled out.
Crossroads President and CEO Steven Law suggested Tuesday that Akin was potentially helping Democrats retain their Senate majority by remaining in the race.
"The stakes in this election are far bigger than any one individual," said Brian Walsh, a spokesman for the National Republican Senatorial Campaign Committee. By staying in the race, Akin "is putting at great risk many of the issues that he and others in the Republican Party are fighting for."
Without that financial backing, Akin will need the support of social conservatives, who have formed his political base through a 12-year congressional career.
Noreen McCann, who lives in the same suburban St. Louis area as Akin, said Tuesday that his rape comment hasn't weakened her support for him. McCann expressed frustration that Akin was being publicly flayed for his ill-chosen words while other Democrats ? specifically President Bill Clinton ? have survived scandals that included accusations of sexual impropriety and lies.
Akin "is a man of principle. I trust and respect his integrity and his commitment to defending American values," said McCann, who had passed out Akin fliers on primary election day. "I think he wants to defend all innocent human life. If he misspoke, or it was in the wrong context, that is not a major problem for me."
But other Missouri Republicans are second-guessing their support for Akin.
Steven and Carolyn Sipes, a pair of retired public school teachers who are GOP committee members in southwest Missouri's Christian County, both voted for Akin in the primary. Carolyn is now doing some soul-searching prayer about whether Akin remains the best choice. Her husband believes Republicans would have a better shot of unseating McCaskill without Akin.
"If he decides to stay in, I'll back him to the hilt," Steven Sipes said. But "I think it would be better probably if he did drop out at this point. He's getting a lot of negative publicity."
Akin's campaign released an open letter Tuesday from Jack Willke, former president of the U.S. National Right to Life Committee, stating he was "outraged at how quickly Republican leaders have deserted" Akin.
Akin "remains a strong and courageous pro-life leader ? and awkward wording in one sound bite doesn't negate that," Willke's statement said.
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Associated Press writers Jim Salter in St. Louis and Henry C. Jackson in Washington contributed to this report.
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