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Friday, August 2, 2013

Doctor K: Study casts doubt on fish oil supplements - Thu, 01 Aug 2013 PST

August 1, 2013 in Features

Anthony L. Komaroff Universal Uclick

DEAR DOCTOR K: I have risk factors for heart disease. I?ve been dutifully taking fish oil supplements for years to reduce my risk of a heart attack. Now I read that they don?t help. Should I stop taking?them?

DEAR READER: Fish oil, loaded with omega-3 fatty acids, has garnered a reputation as an easy way to protect the heart. But a recent study published in the New England Journal of Medicine found that fish oil pills don?t reduce the risk of heart attack and stroke in people at increased?risk.

The new study focused on about??

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The new study focused on about 12,500 people who never had a heart attack or stroke. But they had high blood pressure, a family history of heart disease or other factors that increased their risk. Study participants were randomly divided into two groups. One group took a daily capsule containing omega-3 fatty acids found in fish. The other group took ?dummy? pills that contained olive?oil.

During the next five years, about 12 percent of people in each group died or suffered a heart attack, stroke or other heart-related?problem.

This new study was a very strong one, but it can be?criticized.

For example, there is evidence that olive oil also is heart-healthy. If the truth is that both fish oil capsules and olive oil capsules can protect the heart, then perhaps the study would have been more convincing if fish oil were compared to a capsule with a substance not thought to be heart-healthy. Nevertheless, based on this study, I wouldn?t rely on fish oil pills to lower your risk of heart attack and?stroke.

In the meantime, stick to proven ways to lower your chance of heart attack and?stroke:

? Quit?smoking.

? Exercise?more.

? Eat smaller?portions.

? Decrease saturated fats and eliminate trans?fats.

? Keep your blood pressure in the normal range, with medicines if?needed.

? Lower your LDL cholesterol with medication if?needed.

? Ask your doctor if you should take a baby?aspirin.

Source: http://www.spokesman.com/stories/2013/aug/01/study-casts-doubt-on-fish-oil-supplements/

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Thursday, August 1, 2013

How will Avs fare after new additions from head coach to Jumbotron?

Here are 10 questions that will determine how well the Avalanche does in 2013-14.

1. "Will Patrick Roy really be ready to coach in the NHL?" ? I say yes, yes, a thousand times yes. He's paid his dues. He's ready for his close-up behind the bench. He's going to be very good at this.

2. "What will be the one thing that most accelerates some dark hairs to gray?" ? The defense. It won't be great. Patrick will have to spin a few plates and get the smoke and mirrors just right to make that defense adequate.

3. "Ryan O'Reilly will be a left winger. Is this the wrong decision?" ? Could be. He's been a center his whole life, but now he'll be expected to be the one who changes position for the good of the team. But with Paul Stastny, Matt Duchene and Nathan MacKinnon already here as centers, O'Reilly was the odd-man out.

4. "If O'Reilly doesn't play well, is it a foregone conclusion he'll be traded later in the season?" ? Not necessarily. Both he and Stastny are entering their final contract years, but the Avs would retain O'Reilly's rights after this coming season ends. Not so with Stastny. He can become an unrestricted free agent. If they don't think the numbers on a future deal add up, Stastny would be prime trade bait at the deadline.

5. "Doesn't it look like either Stastny or O'Reilly will have to go at some point soon?" ? Yeah, probably.

6. "Was it more than a little alarming the other day when new goalie coach Francois Allaire was quoted as saying he thinks, after talking with him, that Semyon Varlamov wants to "flush everything out" and start over with new working concepts in goal?" ? Alarming? No, not necessarily. A

Avalanche coach Patrick Roy (John Leyba, Denver Post file)

tad worrisome? Perhaps, but overall I think it's a good thing Varlamov wants to submit to his new teacher with a mind-set of "let's try anything, if it will work." Allaire has a proven track record of turning around the careers of previous goalies, so this development could be one of the best of the summer for the Avs.

7. "Who should be captain of the Avs?" ? With no offense to Gabe Landeskog, I think Matt Duchene has emerged as the real leader of this team. Landeskog would make a great alternate captain, but there were too many things last season that hinted the young Swede was not quite ready. Exhibit A: It should have been Landeskog who went off in the locker room after a late-season, desultory loss to Calgary. Instead, it was left to J.S. Giguere to do it. Maybe Jiggy should really get the "C," except they don't allow goalies to be captains in the NHL.

8. "Is Erik Johnson training himself silly right now, looking like Clubber Lang in 'Rocky III,' ready to prove everyone he's champion material?" ? Just wonderin'.

9. "Is the new Jumbotron going to make going to the Pepsi Center a much better experience?" ? I hear it'll be semi-mind blowing.

10. "How hard will it be to get through all of August with zero hockey talk while you are on vacation?" ? Tough, very tough. But I'll figure out some way to compensate on a beach on Cape Cod very soon.

Until then ... I'll send you all a postcard.

Adrian Dater: 303-954-1360, adater@denverpost.com or twitter.com/adater

Visit denverpost.com each weekday near noontime for a serving of dish concerning Colorado's sporting landscape from a Denver Post sports writer. Care for another helping? Visit the Lunch Special archive.

Source: http://www.denverpost.com/lunchspecial/ci_23768307/how-will-avs-fare-after-new-additions-from?source=rss

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Special Software Lets the NSA Collect "Nearly Everything" You Do Online

Just when you thought the scale of the NSA's surveillance programs couldn't get more superlative, new details about a special software suite show that analysts can access "nearly everything a typical user does on the internet." If it uses HTTP, the NSA can get it.

Family pitches in to save historic Oldham golf course

31 Jul 2013 19:43

Mark Cumisky, 46, wants to add a cafe, driving range and putting green to the Bishop's Park and has already set his wife and three children to work.

A historic golf course has been saved after years in the rough ? and its new owners are? a family whose members are all set to pitch in.

Picturesque Bishop?s Park Pitch and Putt, set 1,233ft above sea level at Grains Bar, Oldham, had closed in October.

Council chiefs, sick of losing money on the Pennine foothills facility, opened it up to offers which sparked fears it may have been demolished.

But the nine-hole course is now to open again after being snapped up by an eagle-eyed Milnrow businessman.

Mark Cumisky, 46, wants to add a cafe, driving range and putting green to the site and has already set his wife and three children to work.

He beat off four other bidders to secure a 25-year lease and is now eyeing similar courses across the region.

Mark, who has worked on golf course construction and maintenance for 20 years, explained: ?I?ve been driving past it for 14 years and I thought it was a real shame the way it had been left to go downhill.

?I saw the lease sign and thought I?d make a go of it.?

Mark, who set up Pennine Golf Ltd with brother Carl, 51, wants to install a 280-yard driving range on a former cricket pitch next door and hopes to start work on it in the winter.

He reopened the 61-year-old course earlier this month and it has already become a family affair. He said: ?My wife, Colette, is going to run the cafe. My daughter, Kim, is working in the booking office while she?s home from university and my son Reece is working on the course with me while he?s off school. My youngest daughter Vicky is painting the tees.?

An agreement has also been reached with the nearby King?s Arms pub to host corporate outings.

Mark said: ?We?ve already had four or five companies interested.?

Coun Shoab Akhtar said: ?The facility was making year on year losses and as a council we decided to advertise it on the open market.

?This is great news for the borough and we?re delighted to grant this initial licence to the new tenant.?

Source: http://feedproxy.google.com/~r/menews/~3/ftRqFqtyooE/family-pitches-save-historic-oldham-5390615

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O.J. Simpson now waits for ruling on new trial

FILE - In this May 16, 2013 file photo, O.J. Simpson listens during an evidentiary hearing in Clark County District Court, Thursday, May 16, 2013 in Las Vegas. Simpson has a hearing before the state parole board Thursday, July 25, 2013, but even a favorable decision won't spring him from prison for his kidnapping and robbery convictions. He was sentenced consecutively on several charges so he would still have more time to serve. (AP Photo/Julie Jacobson, Pool, File)

O.J. Simpson, in custody at the Lovelock Correctional Center, is on the video screen above Nevada Board of Parole hearing representative Robin Bates, left, and Commissioner Susan Jackson during a video conference parole hearing, in Carson City, Nev., on Thursday, July 25, 2013. O.J. Simpson pleaded for leniency Thursday, telling the parole panel he deeply regretted robbing two sports memorabilia dealers. (AP Photo/Nevada Appeal, Geoff Dornan)

CARSON CITY, Nev. (AP) ? After five years behind bars, O.J. Simpson has won a small victory with a Nevada Board of Parole Commissioners decision ? but the former NFL star won't likely be leaving prison anytime soon.

The board on Wednesday approved Simpson's parole request on five concurrent sentences imposed in 2008 following his conviction for kidnapping and armed robbery of two sports memorabilia dealers at a Las Vegas hotel room.

But he still has more time to serve for other sentences ordered to run consecutively.

Simpson faces at least four more years ? and three more parole hearings ? unless Clark County District Judge Linda Marie Bell throws out his conviction and grants him a new trial.

Bell presided over a weeklong hearing in May, during which Simpson's current lawyers Patricia Palm and Ozzie Fumo argued that his trial attorney, Yale Galanter, botched Simpson's defense and had a conflict of interest in the case.

Bell has yet to issue a decision. If she rules in Simpson's favor, prosecutors will have to decide wither to retry him, offer a plea deal, or set him free with credit for time served.

In Wednesday's order granting parole, commissioners cited Simpson's "positive institutional record" and his participation in programs addressing "behavior that led to incarceration."

The board also noted that Simpson had no previous criminal convictions and still has consecutive sentences to serve in the Las Vegas case.

In Los Angeles, Simpson was tried for murder and acquitted in the 1994 deaths of his ex-wife, Nicole Brown Simpson, and her friend Ronald Goldman.

In a statement Wednesday to The Associated Press, Goldman's father and sister, Fred and Kim Goldman, said they respect the legal process but now feel a "sense of vulnerability."

"This is not our personal case against Simpson but since he's been incarcerated there has been a reprieve and calm for us," they said. "It is unsettling for our family to know that the person we believe responsible for Ron and Nicole's murder could soon have his freedom."

Simpson and his legal team were pleased with the ruling.

"We expected it," Palm told the AP shortly after the order was issued. "There is no reason not to grant him parole. I'm glad they did what they should have done."

Palm said Simpson called from prison to let her know of the board's decision.

"He's very happy and grateful," she said.

Simpson appeared before a two-member Nevada parole panel on July 25 to plead for leniency. He expressed regret for his actions and said he's tried to be a model inmate while behind bars.

Simpson was convicted on charges including kidnapping, robbery, burglary and assault with a deadly weapon. He was sentenced to nine to 33 years for the 2007 stickup of two memorabilia dealers, Alfred Beardsley and Bruce Fromong.

During last week's parole hearing, a graying Simpson told Parole Commissioner Susan Jackson and hearing officer Robin Bates, a retired Nevada prison warden, that he was sorry for his actions.

"I just wish I never went to that room," Simpson said. He added that he has made amends with Beardsley and Fromong.

He said he made a promise to the warden when he arrived at Lovelock, 90 miles east of Reno, that he would be the "best person" they ever had at the facility. He added, "I think for the most part I've kept my word on that."

Simpson also said he's acted as jailhouse counselor of sorts to other inmates, some of whom are serving time for similar crimes.

But he said his deed was different.

"They were trying to steal other people's property," Simpson said of other prisoners. "They were trying to steal other people's money. My crime was trying to retrieve for my family my own property."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-08-01-OJ%20Simpson/id-ee8c91f13dea4c8699775f6a6e213d4d

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Tuesday, July 30, 2013

Weight Discrimination May Lead to More Weight Gain

Discriminating against people because of their weight may only increase their likelihood of gaining more weight,?new study shows.

The researchers found that among people who were not obese, those who reported experiencing weight discrimination were 2.5 times more likely to have become obese four years later.

Among people who were obese at the start of the study, those who experienced discrimination were three times more likely to remain obese, compared with those who did not feel discriminated against, the study found.

The results suggest weight discrimination feeds a vicious cycle, in which people who are overweight or obese are likely to experience weight discrimination, which in turn leads to obesity and difficulties with weight management, according to the study, which was published July 24 in the journal?PLOS ONE.?

"Weight discrimination is relatively common," said study researcher Angelina Sutin, professor of psychology at Florida State University College of Medicine. "But the findings suggest that shaming has the opposite effect that people often think."

Previous research shows that experiencing weight bias may lead to depression, low self-esteem and other poor psychological outcomes. In the new study, the researchers didn't test the mechanisms that might be driving the link between discrimination and obesity, but they said they suspect that people who experience weight discrimination are more likely to develop unhealthy behaviors as coping strategies, including binge eating and avoiding physical activity. [11 Surprising Things That Make Us Gain Weight]

Nevertheless, weight bias is one of the most socially accepted forms of discrimination, the researchers said, perhaps justified by the misconception that such discrimination may motivate people to lose weight.

"What's really striking in the study is that not only does weight discrimination increase the risk of obesity, but it's also related to remaining obese over time," said Rebecca Puhl, deputy director at the Rudd Center for Food Policy & Obesity at Yale University. Puhl was not involved in the study.

"In our efforts to address obesity, we need to recognize that stigma poses legitimate barriers and challenges in those efforts," Puhl said.

In recent years, there have been hundreds of anti-obesity campaigns emerging from public health organizations, Puhl said. While many of them stem from positive intentions to improve public health, some are being criticized for shaming and blaming people who are affected by obesity.

"We need to recognize that that's not an effective way to communicate to the public about weight and health," Puhl said.

Puhl and her colleagues have previously studied public reactions to obesity campaigns. They found that campaigns that seemed to resonate the most with the public were those that focused on specific health behaviors that everyone, regardless of their body size, is encourage to follow ? for example, eating more fruits and vegetables, and replacing sugar- and cream-based beverages with water.

"Interestingly, the campaigns that received the most favorable ratings were the ones that didn't even mention obesity," Puhl said.

In the new study, the researchers looked at the heights and weights of more than 6,000 participants, measured in 2006 and 2010.

Participants completed questionnaires that measured perceived discrimination ? for example, whether they felt they were treated with less courtesy and respect than other people. Participants were also asked whether they thought those experiences happened to them because of characteristics including their gender, race and weight.

Discrimination based on other factors, such as sex or race, did not appear to have the same correlation with weight.

"There is a lot of evidence that experiencing weight discrimination is associated with increased risk of maladaptive eating patterns such as binge eating, emotional eating," Sutin said.

There may be direct physiological mechanisms too, she added. The stress caused by discrimination increases the cortisol hormone, which is associated with weight gain.
?

Email Bahar Gholipour or follow her @alterwired. Follow?LiveScience?@livescience, Facebook?& Google+. Original article on LiveScience.com.

Source: http://news.yahoo.com/weight-discrimination-may-lead-more-weight-gain-104800942.html

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Friday, July 26, 2013

Researchers find new way to create 'gradients' for understanding molecular interactions

Public release date: 26-Jul-2013
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Contact: Matt Shipman
matt_shipman@ncsu.edu
919-515-6386
North Carolina State University

Scientists use tools called gradients to understand how molecules interact in biological systems. Researchers from North Carolina State University have developed a new technique for creating biomolecular gradients that is both simpler than existing techniques and that creates additional surface characteristics that allow scientists to monitor other aspects of molecular behavior.

A gradient is a material that has a specific molecule on its surface, with the concentration of the molecule sloping from a high concentration on one end to a low concentration at the other end. The gradient is used not only to determine whether other molecules interact with the molecules on the gradient, but to determine the threshold level at which any interactions take place.

The new technique begins by creating a substrate, prepared in the lab of NC State professor Dr. Salah Bedair, out of the semiconductor material indium gallium nitride (InGaN). The substrate itself is a gradient, sloping from an indium-rich end (with a larger proportion of indium to gallium) to a gallium-rich end. The indium-rich end is more conducive to the formation of oxides. When exposed to humidity, negatively charged indium and gallium oxides form on the surface of the substrate. The substrate development for these purposes was proposed by Dr. Tania Paskova, a professor of electrical and computer engineering at NC State.

The researchers then put the substrate into a solution that contains an amino acid called L-arginine, which is positively charged at biologically relevant pH levels -- such as those found in the human body.

"The L-arginine binds to the negatively charged oxides on the surface of the substrate," says Lauren Bain, a Ph.D. student at NC State who is lead author of a paper on the work. "Because there is more oxide accumulation at the indium-rich end, there is a higher concentration of L-arginine at that end, and the concentration gradually declines along the surface of the substrate as you move toward the gallium-rich end.

"We studied L-arginine because it is small, but relevant. Because it is small, we could easily assess what was happening during our study," Bain says. "But because it is a building block for proteins, we can build on this work to study full peptides and proteins -- such as ligands that bind to cell receptors."

"This technique also creates changes in the topography of the InGaN's surface, based on the different crystalline structures within the material as its shifts from being indium-rich to being gallium-rich," says Dr. Albena Ivanisevic, senior author of the paper. "This allows us to assess topographical differences in molecular adhesion, which is important, given the variety of topographies found in biological systems." Ivanisevic is an associate professor of materials science and engineering at NC State and associate professor of the joint biomedical engineering program at NC State and the University of North Carolina at Chapel Hill.

###

The paper, "Biomolecular Gradients via Semiconductor Gradients: Characterization of Amino Acid Adsorption to InxGa1-xN Surfaces," is published online in ACS Applied Materials and Interfaces. The paper's co-authors include Aadhithya Hosalli Mukund of NC State and Dr. Scott Jewett of Affinergy, LLC.

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Researchers find new way to create 'gradients' for understanding molecular interactions Public release date: 26-Jul-2013
[ | E-mail | Share ]
Contact: Matt Shipman
matt_shipman@ncsu.edu
919-515-6386
North Carolina State University

Scientists use tools called gradients to understand how molecules interact in biological systems. Researchers from North Carolina State University have developed a new technique for creating biomolecular gradients that is both simpler than existing techniques and that creates additional surface characteristics that allow scientists to monitor other aspects of molecular behavior.

A gradient is a material that has a specific molecule on its surface, with the concentration of the molecule sloping from a high concentration on one end to a low concentration at the other end. The gradient is used not only to determine whether other molecules interact with the molecules on the gradient, but to determine the threshold level at which any interactions take place.

The new technique begins by creating a substrate, prepared in the lab of NC State professor Dr. Salah Bedair, out of the semiconductor material indium gallium nitride (InGaN). The substrate itself is a gradient, sloping from an indium-rich end (with a larger proportion of indium to gallium) to a gallium-rich end. The indium-rich end is more conducive to the formation of oxides. When exposed to humidity, negatively charged indium and gallium oxides form on the surface of the substrate. The substrate development for these purposes was proposed by Dr. Tania Paskova, a professor of electrical and computer engineering at NC State.

The researchers then put the substrate into a solution that contains an amino acid called L-arginine, which is positively charged at biologically relevant pH levels -- such as those found in the human body.

"The L-arginine binds to the negatively charged oxides on the surface of the substrate," says Lauren Bain, a Ph.D. student at NC State who is lead author of a paper on the work. "Because there is more oxide accumulation at the indium-rich end, there is a higher concentration of L-arginine at that end, and the concentration gradually declines along the surface of the substrate as you move toward the gallium-rich end.

"We studied L-arginine because it is small, but relevant. Because it is small, we could easily assess what was happening during our study," Bain says. "But because it is a building block for proteins, we can build on this work to study full peptides and proteins -- such as ligands that bind to cell receptors."

"This technique also creates changes in the topography of the InGaN's surface, based on the different crystalline structures within the material as its shifts from being indium-rich to being gallium-rich," says Dr. Albena Ivanisevic, senior author of the paper. "This allows us to assess topographical differences in molecular adhesion, which is important, given the variety of topographies found in biological systems." Ivanisevic is an associate professor of materials science and engineering at NC State and associate professor of the joint biomedical engineering program at NC State and the University of North Carolina at Chapel Hill.

###

The paper, "Biomolecular Gradients via Semiconductor Gradients: Characterization of Amino Acid Adsorption to InxGa1-xN Surfaces," is published online in ACS Applied Materials and Interfaces. The paper's co-authors include Aadhithya Hosalli Mukund of NC State and Dr. Scott Jewett of Affinergy, LLC.

[ | E-mail | Share ]
?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2013-07/ncsu-rfn072613.php
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